Long‐Term Corticosteroid‐Sparing Immunosuppression for Cardiac Sarcoidosis

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Cardiac Sarcoidosis.

Cardiac sarcoidosis (CS) is a rare and under-recognized clinical entity that requires a high level of suspicion and low threshold for screening in order to make the diagnosis. CS may manifest in a variety of ways, and its initial presentation can range from asymptomatic electrocardiographic abnormalities to overt heart failure to sudden cardiac death. The aim of this literature review is to pro...

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Studies suggest clinically manifest cardiac involvement occurs in 5% of patients with pulmonary/systemic sarcoidosis. The principal manifestations of cardiac sarcoidosis (CS) are conduction abnormalities, ventricular arrhythmias, and heart failure. Data indicate that an 20% to 25% of patients with pulmonary/systemic sarcoidosis have asymptomatic (clinically silent) cardiac involvement. An inter...

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Cardiac involvement in sarcoidosis

Sarcoidosis is a systemic disease of unknown aetiology characterised by the formation of noncaseating epitheloid cell granulomas, which can occur in virtually any organ. Cardiac involvement is of critical importance, due to the poor prognosis if this organ manifestation is left undiagnosed and untreated. Early initiation of therapy seems to be associated with a good prognosis; therefore, the di...

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ژورنال

عنوان ژورنال: Journal of the American Heart Association

سال: 2019

ISSN: 2047-9980

DOI: 10.1161/jaha.118.010952